Nicotinamide Adenine Dinucleotide Reduced

Nicotinamide adenine dinucleotide (NAD) is a coenzyme that transports protons (or more precisely hydrogen ions) and participates in many metabolic reactions in cells. NADH or more accurately NADH + H⁺ is its reduced form. It can be reduced to carry up to two protons (written as NADH + H⁺).

β-nicotinamide adenine dinucleotide disodium is a bioactive form of nicotinic acid. It is used as coenzyme of hydrogenase and dehydrogenase. NAD usually acts as a hydrogen receptor to form NADH, which then acts as a hydrogen donor in the respiratory chain. NAD mainly exists in living cells in the reduced form and participates in the synthesis reaction. The compound has 2 diastereomer: α-NAD and β-NAD, which are characterized by the configuration of ribosylnicotinamide bond. Only the β-diastereomer has bioactivity.

NCE can provide β-Nicotinamide Adenine Dinucleotide Disodium Salt, reduced (NADH) with HPLC ≥98% in the packages of grams, kilograms or even larger bulk amounts. Please contact us for more details. Get a Quote Now! For other organic compounds, please check our Organic Compounds catalog page.

Typical Applications:

β-nicotinamide adenine dinucleotide (NAD⁺) and reduced β-nicotinamide adenine dinucleotide (NADH) constitute a coenzyme redox pair (NAD⁺ : NADH), which is involved in a wide range of enzyme catalyzed redox reactions. Besides its redox function, NAD⁺ is a ribose donor in ADP-ribose transfer reactions. The ADP-ribose moiety of NAD⁺ can be transferred to proteins by ADP-ribosyltransferases during ADP-ribosylation. In addition, NAD⁺ also has a function in cell signaling as a precursor of cyclic ADP-ribose.

Inquiries and orders should include the following information:

1. Quantity
2. Purity

Standard Packing: Grams, kilograms, and bulk quantities are available on request

Storage: 2-8 °C